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About NET-PD NET-PD Studies Study News and Publications

For more information about Parkinson's disease research, visit the NINDS PD research page: Current-Research/Focus-Disorders/Parkinsons-Disease

Study News and Publications

Study News

Statement on the Termination of NET-PD LS-1 Study

Study Publications

Parashos SA, Luo S, Biglan KM, Bodis-Wollner I, He B, Liang GS, Ross GW, Tilley BC, Shulman LM; NET-PD Investigators. Measuring disease progression in early Parkinson disease: the National Institutes of Health Exploratory Trials in Parkinson Disease (NET-PD) experience. JAMA Neurol. 2014 Jun;71(6):710-6. doi: 10.1001/jamaneurol.2014.391.

Futility studies:
Annals of Neurology, Feb 2005; 57:197-203 (A Responsive Outcome for Parkinson's Disease Neuroprotection Futility Studies [pdf, 95KB])

Neurology, Mar 2006; 66: 628-633 (Optimizing the ongoing search for new treatments for Parkinson disease: Using futility designs [pdf, 196KB]) (Permission granted by Lippincott Williams & Wilkins)

Neurology, Mar 2006; 66: 626-627 (Futility studies: Spending a little to save a lot [pdf, 268KB]) (Permission granted by Lippincott Williams & Wilkins)

Statistical issues:
Movement Disorders vol 19, Supp 9, 2004, pg S270 Abstract (Statistical Issues in Design of Phase II Futility Studies in Parkinson's Disease (PD)

Movement Disorders vol 19, Supp 9, 2004, pg S233 Abstract (Statistical Issues in Analysis of a large Simple Neuroprotection Trials (LST) in Parkinson's Disease (PD)

Clinical trials infrastructure:
Movement Disorders vol 19, Supp 9, 2004, pg S198 Abstract (Do Clinical Trial Infrastructures Impact Enrollment Rates and Baseline Demographics in Early Parkinson's Disease (PD) Studies?)